Remove element with class name

How can I remove the element that has the class loader?

<app-user>
<app-supp>
<ngx-supp>
<div class="ngx-supp">
<div class="loader">...</div>
<div class="mode">...</div>
</div>
</ngx-supp>
</app-supp>
</app-user>

Continue reading...