I am trying to update values in an excel sheet using Pandas but the changes overwrites the whole file instead of just a value in in a sheet. sheet_1 = pd.read_excel(r"Documents\TestPage.xlsx", 0) sheet_1.loc[0, 'Test1'] = 10 sheet_1.to_excel("Documents\TestPage.xlsx", sheet_name= 'sheet_1') My code intends to change only Test1 value but instead it overwrites the entire new file losing other pages. I noticed that others facing similar issues but I could figure out looking at the answer. Appreciate your help and guidance. Cheer Continue reading...