[Python] working with HUGE lists in python

how can I manage a huge list of 100+ million strings? How can i begin to work with such a huge list?

example large list:

cards = [
"2s","3s","4s","5s","6s","7s","8s","9s","10s","Js","Qs","Ks","As"
"2h","3h","4h","5h","6h","7h","8h","9h","10h","Jh","Qh","Kh","Ah"
"2d","3d","4d","5d","6d","7d","8d","9d","10d","Jd","Qd","Kd","Ad"
"2c","3c","4c","5c","6c","7c","8c","9c","10c","Jc","Qc","Kc","Ac"
]

from itertools import combinations

cardsInHand = 7
hands = list(combinations(cards, cardsInHand))

print str(len(hands)) + " hand combinations in texas holdem poker"

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