When a Python script is supposed to be run from a pyenv virtualenv, what is the correct shebang for the file? As an example test case, the default Python on my system (OS X) does not have pandas installed. The pyenv virtualenv venv_name does. I tried getting the path of the Python executable from the virtualenv. pyenv activate venv_name which python Output: /Users/username/.pyenv/shims/python So I made my example script.py: #!/Users/username/.pyenv/shims/python import pandas as pd print 'success' But when I tried running the script (from within 'venv_name'), I got an error: ./script.py Output: ./script.py: line 2: import: command not found ./script.py: line 3: print: command not found Although running that path directly on the command line (from within 'venv_name') works fine: /Users/username/.pyenv/shims/python script.py Output: success And: python script.py # Also works Output: success What is the proper shebang for this? Ideally, I want something generic so that it will point at the Python of whatever my current venv is. Continue reading...