I'm working on creating some scripts for our team to use with some new sensitivity labels that were recently implemented. I ultimately need a script that will get the current classification, and a script that will set the classification. I have the script that returns the GUID of the sensitivity label, and that functions fine. I'm having issues when I'm trying to run SensitivityLabel.SetLabel though. Here is what I've been trying to use to set the sensitivity label (unsuccessfully). import win32com.client as win32 import os file = os.path.join(os.getcwd() + book) excel = win32.gencache.EnsureDispatch("Excel.Application") excel.DisplayAlerts = False excel.Visible = False try: workbook = excel.Workbooks.Open(file) except Exception as e: print(e) workbook = None assert workbook != None workbook.Activate label = workbook.SensitivityLabel.CreateLabelInfo() label.LabelId = 'guid here, verified by getLabel function' workbook.SensitivityLabel.SetLabel(label,label) excel.ActiveWorkbook.Save() excel.ActiveWorkbook.Close(True) excel.Application.Quit() workbook = None excel = None I thought that this would be sufficient, as its what I've seen others using and it seems to work there - but I'm getting a com_error. ' --------------------------------------------------------------------------- com_error Traceback (most recent call last) Cell In[19], line 34 32 label = workbook.SensitivityLabel.CreateLabelInfo() 33 label.LabelId = '6d47f64f-b290-43a1-b909-b6568bad646' ---> 34 workbook.SensitivityLabel.SetLabel(label,label) 36 excel.ActiveWorkbook.Save() 37 excel.ActiveWorkbook.Close(True) File <COMObject SensitivityLabel>:2, in SetLabel(self, LabelInfo, Context) com_error: (-2147352567, 'Exception occurred.', (0, None, None, None, 0, -2147467259), None) ' Continue reading...