I am trying to run stitchr in R. For programs that run in Python, I use reticulate. I create a conda environment named r-reticulate, where I want to install stitchr and run it. I try the following: if (!('r-reticulate' %in% reticulate::conda_list()[,1])){ reticulate::conda_create(envname = 'r-reticulate', packages = 'python=3.10') } reticulate::use_condaenv('r-reticulate') reticulate:y_install("stitchr", pip = TRUE) system("stitchr -h") # this does not work But obviously enough, the system() call does not work, with the message error in running command. What would be the right way to do this? I had success in the past with anndata, for example. But this is an R package wrapper, so I can just do: reticulate::use_condaenv('r-reticulate') reticulate:y_install("anndata", pip = TRUE) data_h5ad <- anndata::read_h5ad("file.h5ad") How can I approach the stitchr case? EDIT: So I retrieved stitchr.py location during the package installation: /usr/local/Caskroom/miniconda/base/envs/r-reticulate/lib/python3.10/site-packages/Stitchr/stitchr.py I tried all the following but nothing works (see error messages): pyloc="/usr/local/Caskroom/miniconda/base/envs/r-reticulate/lib/python3.10/site-packages/Stitchr/stitchr.py" reticulate::source_python(pyloc) Error in py_run_file_impl(file, local, convert) : ImportError: attempted relative import with no known parent package Run reticulate:y_last_error() for details. reticulate:y_run_file(pyloc) Error in py_run_file_impl(file, local, convert) : ImportError: attempted relative import with no known parent package Run reticulate:y_last_error() for details. reticulate:y_run_string(paste(pyloc, "-h")) Error in py_run_string_impl(code, local, convert) : File "", line 1 /usr/local/Caskroom/miniconda/base/envs/r-reticulate/lib/python3.10/site-packages/Stitchr/stitchr.py -h SyntaxError: invalid syntax Run reticulate:y_last_error() for details. I am absolutely clueless on how to proceed here. Continue reading...