I'm trying to use Matplotlib on RHEL using a pyenv installed version of python 3.6.5. (installed using the following command) → pyenv install 3.6.5 Installing Python-3.6.5... python-build: use readline from homebrew Installed Python-3.6.5 to /home/swp1g17/.pyenv/versions/3.6.5 → pyenv global 3.6.5 I'm presented with the following error, and have found many questions that have a similar issue: Python 3.6.5 (default, Apr 5 2018, 17:22:36) [GCC 5.5.0] on linux Type "help", "copyright", "credits" or "license" for more information. >>> import tkinter Traceback (most recent call last): File "<stdin>", line 1, in <module> File "/home/swp1g17/.pyenv/versions/3.6.5/lib/python3.6/tkinter/__init__.py", line 36, in <module> import _tkinter # If this fails your Python may not be configured for Tk ModuleNotFoundError: No module named '_tkinter' However the suggested solution is usually to install tkinter using a package manager. However I've tried installing: 2872 sudo yum install rh-python36-python-tkinter 2873 sudo yum install rh-python35-python-tkinter 2874 sudo yum install rh-python34-python-tkinter 2891 sudo yum install tkinter 2893 sudo yum install python36-tkinter 2902 sudo yum install gcc zlib-devel bzip2 bzip2-devel readline-devel sqlite sqlite-devel openssl-devel tk-devel gdbm-devel ncurses-devel gl.. 2916 sudo yum install tkinter.x86_64 rh-python36-python-tkinter.x86_64 rh-python35-python-tkinter.x86_64 rh-python34-python-tkinter.x86_64 p.. 2921 sudo yum install tcl 2933 sudo yum install tk-devel 2934 sudo yum install tk 3000 sudo yum install tkinter 3026 sudo yum install tix 3031 sudo yum install tk 3032 sudo yum install tk-devel > 3033 sudo yum install tcl-devel with each already having been installed or making no difference (having rebuilt python each time a new package was installed. The system python is able to locate tkinter: → /usr/bin/python3.6 Python 3.6.3 (default, Jan 4 2018, 16:40:53) [GCC 4.8.5 20150623 (Red Hat 4.8.5-16)] on linux Type "help", "copyright", "credits" or "license" for more information. >>> import tkinter >>> so I'm unsure how to install python using pyenv and have it use the same version of tkinter? UPDATE: Having found that build configuration options can be set using $PYTHON_CONFIGURE_OPTS I've tried specifying the library locations using (for linuxbrew downloaded tcl/tk): export PYTHON_CONFIGURE_OPTS="--with-tcltk-includes=-I/home/linuxbrew/.linuxbrew/opt/tcl-tk/include --with-tcltk-libs=-L/home/linuxbrew/.linuxbrew/opt/tcl-tk/lib" pyenv install 3.6.5 and (using system tcl/tk): export PYTHON_CONFIGURE_OPTS="--with-tcltk-includes=-I/usr/include --with-tcltk-libs=-L/usr/lib64" pyenv install 3.6.5 each with no luck. System tcl/tk was found using: → whereis tcl tcl: /usr/lib64/tcl8.5 /usr/include/tcl.h /usr/share/tcl8.5 → whereis tcl tcl: /usr/lib64/tcl8.5 /usr/include/tcl.h /usr/share/tcl8.5 Continue reading...