I have a simple pandas pyinstaller exe which is over 40MB. My exe example: import collections import csv import selenium import pandas print('hi') 40MB+ for this seems a bit overkill. How can I reduce this as much as possible? One method: pyinstaller --onefile --exclude matplotlib --exclude scipy --exclude pandas --exclude numpy.py This however is not practical considering how big the exclusion list would be. How do I select a folder for pyinstaller to get modules from and exclude everything else so I may have a small application? Spec file: a = Analysis(['123.py'], pathex=['C:\\Users\\AA\\ZZ'], binaries=[], datas=[], hiddenimports=[], hookspath=[], runtime_hooks=[], excludes=[], win_no_prefer_redirects=False, win_private_assemblies=False, cipher=block_cipher) pyz = PYZ(a.pure, a.zipped_data, cipher=block_cipher) exe = EXE(pyz, a.scripts, a.binaries, a.zipfiles, a.datas, name='123', debug=False, strip=False, upx=True, runtime_tmpdir=None, console=True ) It's also worth mentioning. By default, Pyinstaller does not detect pandas. Add: hiddenimports = ['pandas._libs.tslibs.timedeltas'] To: C:\Users\<NAME>\AppData\Local\Programs\Python\Python36\Lib\site-packages\PyInstaller\hooks A possible solution when using multiple executables, could be to link each executable to a separate folder or executable with all imports. Continue reading...