This problem is similar to QML module not found when using KDE Kirigami , but in this case, setting the QML_IMPORT_PATH env var before running the pyhton file doesn't solve the problem. I have this simple application: main.py #!/usr/bin/python3 from PySide2.QtWidgets import * from PySide2.QtGui import * from PySide2.QtQml import QQmlApplicationEngine from PySide2.QtCore import * if __name__ == "__main__": # Launch application app = QApplication() engine = QQmlApplicationEngine() context = engine.rootContext() engine.load("content/ui/main.qml") if len(engine.rootObjects()) == 0: quit() win = engine.rootObjects()[0] app.exec_() main.qml // Includes relevant modules used by the QML import QtQuick 2.6 import QtQuick.Controls 2.0 as Controls import QtQuick.Layouts 1.2 import org.kde.kirigami 2.13 as Kirigami // Base element, provides basic features needed for all kirigami applications Kirigami.ApplicationWindow { // ID provides unique identifier to reference this element id: root // Window title // i18nc is useful for adding context for translators, also lets strings be changed for different languages title: i18nc("@title:window", "Hello World") // Initial page to be loaded on app load pageStack.initialPage: Kirigami.Page { Controls.Label { // Center label horizontally and vertically within parent element anchors.centerIn: parent text: i18n("Hello World!") } } } Before running it, I installed all the required dependencies as explained in https://develop.kde.org/docs/use/kirigami/introduction-getting_started/ sudo apt install build-essential extra-cmake-modules cmake qtbase5-dev qtdeclarative5-dev libqt5svg5-dev qtquickcontrols2-5-dev qml-module-org-kde-kirigami2 kirigami2-dev libkf5i18n-dev gettext libkf5coreaddons-dev qml-module-qtquick-layouts The kirigami2 module is present at path /usr/lib/x86_64-linux-gnu/qt5/qml/org/kde/kirigami.2 Btw, when executing the Python file I obtain QQmlApplicationEngine failed to load component file:///home/danieleverducci/git/KDE/python/prova-kirigami/content/ui/main.qml:5:1: module "org.kde.kirigami" is not installed Setting the QML_IMPORT_PATH env var doesn't fix the problem. What am I overlooking? Continue reading...