Over the last few days, I have been working on automating the generation of some pivot tables for a number of reports. Boiled down to the minimum, the following code was working without issue: import win32com.client objExcelApp = win32com.client.gencache.EnsureDispatch('Excel.Application') objExcelApp.Visible = 1 This would pop-up an instance of excel and I could continue working in Python. But suddenly, today my scripts are failing with the following: >>>import win32com.client >>> objExcelApp = win32com.client.gencache.EnsureDispatch('Excel.Application') Traceback (most recent call last): File "<stdin>", line 1, in <module> File "C:\Program Files (x86)\Python37-32\lib\site-packages\win32com\client\gencache.py", line 534, in EnsureDispatch mod = EnsureModule(tla[0], tla[1], tla[3], tla[4], bForDemand=bForDemand) File "C:\Program Files (x86)\Python37-32\lib\site-packages\win32com\client\gencache.py", line 391, in EnsureModule module = GetModuleForTypelib(typelibCLSID, lcid, major, minor) File "C:\Program Files (x86)\Python37-32\lib\site-packages\win32com\client\gencache.py", line 266, in GetModuleForTypelib AddModuleToCache(typelibCLSID, lcid, major, minor) File "C:\Program Files (x86)\Python37-32\lib\site-packages\win32com\client\gencache.py", line 552, in AddModuleToCache dict = mod.CLSIDToClassMap AttributeError: module 'win32com.gen_py.00020813-0000-0000-C000-000000000046x0x1x9' has no attribute 'CLSIDToClassMap' The code has not changed from yesterday to today. I have no idea what is happening!!!. Another interesting kicker. if I do the same code in the same session again I get a different error: >>> objExcelApp = win32com.client.gencache.EnsureDispatch('Excel.Application') Traceback (most recent call last): File "<stdin>", line 1, in <module> File "C:\Program Files (x86)\Python37-32\lib\site-packages\win32com\client\gencache.py", line 534, in EnsureDispatch mod = EnsureModule(tla[0], tla[1], tla[3], tla[4], bForDemand=bForDemand) File "C:\Program Files (x86)\Python37-32\lib\site-packages\win32com\client\gencache.py", line 447, in EnsureModule if module.MinorVersion != tlbAttributes[4] or genpy.makepy_version != module.makepy_version: AttributeError: module 'win32com.gen_py.00020813-0000-0000-C000-000000000046x0x1x9' has no attribute 'MinorVersion' >>> So I jump over to a windows machine with a fresh windows install, install python37 and pip install pypiwin32. Run the very same lines and excel opens just like it did yesterday on my original machine. I tried un-installing and re-installing with no luck. Any idea what is going on here? NOTE: Dynamic dispatch still works: import win32com.client objExcelApp = win32com.client.Dispatch("Excel.Application") objExcelApp.Visible = 1 But I specifically need static dispatch as Pivot Tables won't work with a dynamically dispatched object (much later in my code): objExcelPivotCache = objExcelWorkbook.PivotCaches().Create(SourceType=win32c.xlDatabase, SourceData=objExcelPivotSourceRange) Continue reading...