I have this script: from pycaw.pycaw import AudioUtilities, IAudioEndpointVolume from ctypes import cast, POINTER from comtypes import CLSCTX_ALL, CoInitialize, CoUninitialize CLSCTX_ALL = 7 import time def set_windows_volume(value_max_100): devices = AudioUtilities.GetSpeakers() interface = devices.Activate(IAudioEndpointVolume._iid_, CLSCTX_ALL, None) volume = cast(interface, POINTER(IAudioEndpointVolume)) scalarVolume = int(value_max_100) / 100 volume.SetMasterVolumeLevelScalar(scalarVolume, None) def get_windows_volume(): devices = AudioUtilities.GetSpeakers() interface = devices.Activate(IAudioEndpointVolume._iid_, CLSCTX_ALL, None) windows_volume = cast(interface, POINTER(IAudioEndpointVolume)) volume_percentage = int(round(windows_volume.GetMasterVolumeLevelScalar() * 100)) return volume_percentage for i in range(0,100): set_windows_volume(i) time.sleep(2) print(get_windows_volume()) but sometimes it raises errors: Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable ======== Running on http://192.168.1.188:8080 ======== Exception ignored in: <function _compointer_base.__del__ at 0x000002B538E96B90> Traceback (most recent call last): File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 426, in __del__ self.Release() File "C:\Python\lib\site-packages\comtypes\_post_coinit\unknwn.py", line 559, in Release return self.__com_Release() # type: ignore ValueError: COM method call without VTable Basically i use this script in a multiprocessing.Process with CoInitialize and CoUninitialize and safe release, but the error is still there. Any help or alternatives? Continue reading...