I am trying to use ExcelWriter to write/add some information into a workbook that contains multiple sheets. First time when I use the function, I am creating the workbook with some data. In the second call, I would like to add some information into the workbook in different locations into all sheets. def Out_Excel(file_name,C,col): writer = pd.ExcelWriter(file_name,engine='xlsxwriter') for tab in tabs: # tabs here is provided from a different function that I did not write here to keep it simple and clean df = DataFrame(C) # the data is different for different sheets but I keep it simple in this case df.to_excel(writer,sheet_name = tab, startcol = 0 + col, startrow = 0) writer.save() In the main code I call this function twice with different col to print out my data in different locations. Out_Excel('test.xlsx',C,0) Out_Excel('test.xlsx',D,10) But the problem is that doing so the output is just the second call of the function as if the function overwrites the entire workbook. I guess I need to load the workbook that already exists in this case? Any help? Continue reading...