Checking out how to implement binning with Python polars, I can easily calculate aggregates for individual columns: import polars as pl import numpy as np t, v = np.arange(0, 100, 2), np.arange(0, 100, 2) df = pl.DataFrame({"t": t, "v0": v, "v1": v}) df = df.with_columns((pl.datetime(2022,10,30) + pl.duration(seconds=df["t"])).alias("datetime")).drop("t") df.group_by_dynamic("datetime", every="10s").agg(pl.col("v0").mean()) shape: (10, 2) ┌─────────────────────┬──────┐ │ datetime ┆ v0 │ │ --- ┆ --- │ │ datetime[μs] ┆ f64 │ ╞═════════════════════╪══════╡ │ 2022-10-30 00:00:00 ┆ 4.0 │ │ 2022-10-30 00:00:10 ┆ 14.0 │ │ 2022-10-30 00:00:20 ┆ 24.0 │ │ 2022-10-30 00:00:30 ┆ 34.0 │ │ ... ┆ ... │ or calculate multiple aggregations like df.group_by_dynamic("datetime", every="10s").agg( pl.col("v0").mean().alias("v0_binmean"), pl.col("v0").count().alias("v0_bincount") ) ┌─────────────────────┬────────────┬─────────────┐ │ datetime ┆ v0_binmean ┆ v0_bincount │ │ --- ┆ --- ┆ --- │ │ datetime[μs] ┆ f64 ┆ u32 │ ╞═════════════════════╪════════════╪═════════════╡ │ 2022-10-30 00:00:00 ┆ 4.0 ┆ 5 │ │ 2022-10-30 00:00:10 ┆ 14.0 ┆ 5 │ │ 2022-10-30 00:00:20 ┆ 24.0 ┆ 5 │ │ 2022-10-30 00:00:30 ┆ 34.0 ┆ 5 │ │ ... ┆ ... ┆ ... │ or calculate one aggregation for multiple columns like cols = [c for c in df.columns if "datetime" not in c] df.group_by_dynamic("datetime", every="10s").agg( pl.col(f"{c}").mean().alias(f"{c}_binmean") for c in cols ) ┌─────────────────────┬────────────┬────────────┐ │ datetime ┆ v0_binmean ┆ v1_binmean │ │ --- ┆ --- ┆ --- │ │ datetime[μs] ┆ f64 ┆ f64 │ ╞═════════════════════╪════════════╪════════════╡ │ 2022-10-30 00:00:00 ┆ 4.0 ┆ 4.0 │ │ 2022-10-30 00:00:10 ┆ 14.0 ┆ 14.0 │ │ 2022-10-30 00:00:20 ┆ 24.0 ┆ 24.0 │ │ 2022-10-30 00:00:30 ┆ 34.0 ┆ 34.0 │ │ ... ┆ ... ┆ ... │ However, combining both approaches fails! df.group_by_dynamic("datetime", every="10s").agg( [ pl.col(f"{c}").mean().alias(f"{c}_binmean"), pl.col(f"{c}").count().alias(f"{c}_bincount") ] for c in cols ) DuplicateError: column with name 'literal' has more than one occurrences Is there a "polarustic" approach to calculate multiple statistical parameters for multiple (all) columns of the dataframe in one go? related, pandas-specific: Python pandas groupby aggregate on multiple columns Continue reading...