Suppose I have a Python dict of lists like so: {'Grp': ['2' , '6' , '6' , '5' , '5' , '6' , '6' , '7' , '7' , '6'], 'Nums': ['6.20', '6.30', '6.80', '6.45', '6.55', '6.35', '6.37', '6.36', '6.78', '6.33']} I can easily group the numbers and group key using itertools.groupby: from itertools import groupby for k, l in groupby(zip(di['Grp'], di['Nums']), key=lambda t: t[0]): print k, [t[1] for t in l] Prints: 2 ['6.20'] 6 ['6.30', '6.80'] # one field, key=6 5 ['6.45', '6.55'] 6 ['6.35', '6.37'] # second 7 ['6.36', '6.78'] 6 ['6.33'] # third Note the 6 key is separated into three separate groups or fields . Now suppose I have the equivalent Pandas DataFrame to my dict (same data, same list order and same keys): Grp Nums 0 2 6.20 1 6 6.30 2 6 6.80 3 5 6.45 4 5 6.55 5 6 6.35 6 6 6.37 7 7 6.36 8 7 6.78 9 6 6.33 If I use Pandas' groupby I am not seeing how to get group by group iteration. Instead, Pandas groups by key value: for e in df.groupby('Grp'): print e Prints: ('2', Grp Nums 0 2 6.20) ('5', Grp Nums 3 5 6.45 4 5 6.55) ('6', Grp Nums 1 6 6.30 2 6 6.80 # df['Grp'][1:2] first field 5 6 6.35 # df['Grp'][5:6] second field 6 6 6.37 9 6 6.33) # df['Grp'][9] third field ('7', Grp Nums 7 7 6.36 8 7 6.78) Note are the 6 group keys are bunched together; not separate groups. My question: Is there an equivalent way to use Pandas' groupby so that 6, for example, would be in three groups in the same fashion as Python's groupby? I tried this: >>> df.reset_index().groupby('Grp')['index'].apply(lambda x: np.array(x)) Grp 2 [0] 5 [3, 4] 6 [1, 2, 5, 6, 9] # I *could* do a second groupby on this... 7 [7, 8] Name: index, dtype: object But it is still grouped by overall Grp key and I would need to do a second groupby on the nd.array to split the sub groups of each key out. Continue reading...