[Python] how to set matplotlib figsize using axes and subplots

Hello I have a very basic plot with matplotlib but I want to be able to set the figure size I am confused about how to do this when not using multiple subplots. I am confused about the relationship between the figsize and subplots see code below:

plt.figure(figsize=(10,10))

y = np.arange(1,6,1)
y1 = y**2
y2 = y**3
y3 = y**4
x = np.arange(1,101,20)

fig, ax = plt.subplots()
ax.plot(x,y1)
ax.plot(x,y2)
ax.plot(x,y3)

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