[Python] How to replace NaN values in a dataframe column

I have a Pandas Dataframe as below:

itm Date Amount
67 420 2012-09-30 00:00:00 65211
68 421 2012-09-09 00:00:00 29424
69 421 2012-09-16 00:00:00 29877
70 421 2012-09-23 00:00:00 30990
71 421 2012-09-30 00:00:00 61303
72 485 2012-09-09 00:00:00 71781
73 485 2012-09-16 00:00:00 NaN
74 485 2012-09-23 00:00:00 11072
75 485 2012-09-30 00:00:00 113702
76 489 2012-09-09 00:00:00 64731
77 489 2012-09-16 00:00:00 NaN


When I try to apply a function to the Amount column, I get the following error:

ValueError: cannot convert float NaN to integer


I have tried applying a function using math.isnan, pandas' .replace method, .sparse data attribute from pandas 0.9, if NaN == NaN statement in a function; I have also looked at this Q/A; none of them works.

How do I do it?

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