I have a dataframe as below and I want remove the duplicates and want the out put as mentioned below. Tried few things but not working as expected. New to pandas. import pandas as pd # Sample DataFrame data = { "some_id": "xxx", "some_email": "abc.xyz@somedomain.com", "This is Sample": [ { "a": "22", "b": "Y", "c": "33", "d": "x" }, { "a": "44", "b": "N", "c": "55", "d": "Y" }, { "a": "22", "b": "Y", "c": "33", "d": "x" }, { "a": "44", "b": "N", "c": "55", "d": "Y" }, { "a": "22", "b": "Y", "c": "33", "d": "x" }, { "a": "44", "b": "N", "c": "55", "d": "Y" } ] } df = pd.DataFrame(data) print(df) The output is some_id some_email This is Sample 0 xxx abc.xyz@somedomain.com {'a': '22', 'b': 'Y', 'c': '33', 'd': 'x'} 1 xxx abc.xyz@somedomain.com {'a': '44', 'b': 'N', 'c': '55', 'd': 'Y'} 2 xxx abc.xyz@somedomain.com {'a': '22', 'b': 'Y', 'c': '33', 'd': 'x'} 3 xxx abc.xyz@somedomain.com {'a': '44', 'b': 'N', 'c': '55', 'd': 'Y'} 4 xxx abc.xyz@somedomain.com {'a': '22', 'b': 'Y', 'c': '33', 'd': 'x'} 5 xxx abc.xyz@somedomain.com {'a': '44', 'b': 'N', 'c': '55', 'd': 'Y'} I want to remove duplicates and the output should look like some_id some_email This is Sample 0 xxx abc.xyz@somedomain.com {'a': '22', 'b': 'Y', 'c': '33', 'd': 'x'} 1 xxx abc.xyz@somedomain.com {'a': '44', 'b': 'N', 'c': '55', 'd': 'Y'} How can this be achieved? I tried multiple ways some times it fails with unhashable dict. I have pretty big nested data frame like this. I am using pandas dataframe and python. New to this technology Continue reading...