[Python] How to get the physical interface IP address from an interface

What I have done so far, using PyQt classes:

all_Addresses = QNetworkInterface.allAddresses() #list-of-QHostAddress

for addr in all_Addresses:
print(addr.toString())


Output:

172.16.0.186 - Virtual Interface IP address
192.168.10.2 - Physical interface IP address. I want this one.
127.0.0.1


Using socket:

import socket
print(socket.gethostbyname(socket.gethostname()))


Output:

172.16.0.186 - When openVPN is on
192.168.10.2 - When its off

1. Is there a way to distinguish between them?
2. Can this be done with ordinary Python, instead of using PyQt classes?
3. How can I get the IPv6 address as well?

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