I am calculating the open-high-low-close (OHLC) of data for a duration of each 15 mins from 9:15 to 15:30 and want to store the OHLC values in a dataframe in each new row. ohlc = pd.DataFrame(columns=('Open','High','Low','Close')) for row in ohlc: ohlc.loc[10] = pd.DataFrame([[candle_open_price,candle_high_price,candle_low_price,candle_close_price]]) But I am not able to do say getting an error of: ValueError: cannot set a row with mismatched columns Just I want to incrementally store the OHLC data of each 15-minute duration which I have calculated & put in rows of the new ohlc dataframe EDIT import numpy as np import pandas as pd import datetime as dt import matplotlib as plt import dateutil.parser tradedata = pd.read_csv('ICICIBANK_TradeData.csv', index_col=False, names=['Datetime','Price'], header=0) tradedata['Datetime'] = pd.to_datetime(tradedata['Datetime']) first_trd_time = tradedata['Datetime'][0] last_time = dateutil.parser.parse('2016-01-01 15:30:00.000000') candle_time = 15; candle_number = 0 while(first_trd_time < last_time): candledata = tradedata[(tradedata['Datetime']>first_trd_time) & (tradedata['Datetime']<first_trd_time+dt.timedelta(minutes=candle_time))] first_trd_time = first_trd_time+dt.timedelta(minutes=candle_time) candle_open_price = candledata.iloc[0]['Price'] candle_open_time = candledata.iloc[0]['Datetime'] candle_close_price = candledata.iloc[-1]['Price'] candle_close_time = candledata.iloc[-1]['Datetime'] candle_high_price = candledata.loc[candledata['Price'].idxmax()]['Price'] candle_high_time = candledata.loc[candledata['Price'].idxmax()]['Datetime'] candle_low_price = candledata.loc[candledata['Price'].idxmin()]['Price'] candle_low_time = candledata.loc[candledata['Price'].idxmin()]['Datetime'] ohlc = pd.DataFrame(columns=('Open','High','Low','Close')) ohlc_data = pd.DataFrame() if(candle_number == 0): ohlc = pd.DataFrame(np.array([[0, 0, 0, 0]]), columns=['Open', 'High', 'Low', 'Close']).append(ohlc, ignore_index=True) candle_number = candle_number + 1 print "Zeroth Candle" else: ohlc.ix[candle_number] = (candle_open_price,candle_open_price,candle_open_price,candle_open_price) print "else part with incermenting candle_number" candle_number = candle_number + 1 print "first_trd_time" print first_trd_time print candle_number print "Success!" This is my code error is ValueError: cannot set by positional indexing with enlargement Continue reading...