I know the following about various python HTTP libraries: Requests does not support HTTP/2 requests. Hyper does support HTTP/2 requests, but is archived as of early 2021 and wouldn't be a good choice for new projects. HTTPX does support HTTP/2, but this support is optional, requires installing extra dependencies, and comes with some caveats about rough edges. AIOHTTP does not support HTTP2 yet (as of mid April 2022). The focus of this project is also not solely on being a client -- this package also includes a server. The other major HTTP request library I'm aware of is urllib3. This is what OpenAPI Generator uses by default when generating python client libraries. My Questions are: Can urrlib3 be configured to make HTTP/2 requests? I cannot find any information on http2 support in the documentation, and through my testing of a generated OpenAPI client, all requests are HTTP/1.1. If the answer is no currently, are the maintainers planning HTTP/2 support? I cannot find any evidence of this in the project's open issues. Continue reading...