I am trying to access a physical RS-422 serial port (D-Sub 9) from WSL2 on Windows 11 Pro Version 23H2 (Build 22631.5189) using Python. This is not a USB serial device — it is a real COM port. The industrial PC has four dedicated physical COM ports. What I see: The device works fine when connecting from native Windows using COM1. In WSL2, /dev/ttyS0 through /dev/ttyS3 are visible. I tried connecting via all of them, but none of them work. I have checked the Windows registry for the serial device map and it looks fine. I know about usbipd for USB devices Ideally, I want to run a Python script in a Docker container (inside WSL2) that connects to the device via serial communication. Is it possible to connect to a physical COM port in WSL2 using Python? If so, how can I correctly map or access it? Continue reading...
